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A six-year longitudinal study identifies a statin-independent association between low LDL-cholesterol and risk of type 2 diabetes

Abstract Background Statin therapy has been associated with increased risk of type 2 diabetes (T2D). We investigated the relationship between Low-Density Lipoprotein Cholesterol (LDL-C) plasma concentrations and incident T2D and evaluated the modifying effect of statin therapy in a large population-...

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Principais autores: Maria Lembo, Valentina Trimarco, Daniela Pacella, Raffaele Izzo, Stanislovas S. Jankauskas, Roberto Piccinocchi, Paola Gallo, Luca Bardi, Gaetano Piccinocchi, Carmine Morisco, Stefano Cristiano, Giovanni Esposito, Giuseppe Giugliano, Maria Virginia Manzi, Gaetano Santulli, Bruno Trimarco
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-11-01
Serier:Cardiovascular Diabetology
Fag:
Cardiovascular endocrinology
Cholesterol
Lipid-lowering therapy
Diabetes
Dyslipidemia
Statins
Online adgang:https://doi.org/10.1186/s12933-025-02964-6
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