Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells

Summary: CD226 plays a vital role in natural killer (NK) cell cytotoxicity, interacting with its ligands CD112 and CD155 to initiate immune synapse formation, primarily through leukocyte function-associated-1 (LFA-1). Our study examined the role of CD226 in NK cell surveillance of acute myeloid leuk...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Luciana Melo Garcia, Achintyan Gangadharan, Pinaki Banerjee, Ye Li, Andy G.X. Zeng, Hind Rafei, Paul Lin, Bijender Kumar, Sunil Acharya, May Daher, Luis Muniz-Feliciano, Gary M. Deyter, Gabriel Dominguez, Jeong Min Park, Francia Reyes Silva, Ana Karen Nunez Cortes, Rafet Basar, Nadima Uprety, Mayra Shanley, Mecit Kaplan, Enli Liu, Elizabeth J. Shpall, Katayoun Rezvani
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2025-01-01
סדרה:	Cell Reports
נושאים:	CP: Immunology CP: Cancer
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2211124724014736
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!