EXD2: A new regulator of mitochondrial translation and potential target for cancer therapy

In recent work we identified Exonuclease 3′−5′ domain-containing protein 2 (EXD2) as an RNase required for efficient mitochondrial translation. Here I describe in brief the cellular phenotypes caused by EXD2 deficiency and make the case that EXD2 inhibitors could be valuable agents for cancer therap...

詳細記述

書誌詳細

第一著者:	Travis H. Stracker
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis Group 2018-05-01
シリーズ:	Molecular & Cellular Oncology
主題:	exd2 mitochondria metabolic reprogramming metformin cancer metabolism translation glutamine biology of malignant cells cancer stem cells mode of action of anticancer agents tumor metabolism
オンライン･アクセス:	http://dx.doi.org/10.1080/23723556.2018.1445943
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!