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NAT10-Mediated N4-Acetylcytidine of RNA Contributes to Post-transcriptional Regulation of Mouse Oocyte Maturation in vitro

N4-acetylcytidine (ac4C), a newly identified epigenetic modification within mRNA, has been characterized as a crucial regulator of mRNA stability and translation efficiency. However, the role of ac4C during oocyte maturation, the process mainly controlled via post-transcriptional mechanisms, has not...

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Principais autores: Yuting Xiang, Chuanchuan Zhou, Yanyan Zeng, Qi Guo, Jiana Huang, Taibao Wu, Jiawen Liu, Qiqi Liang, Haitao Zeng, Xiaoyan Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-07-01
coleção:Frontiers in Cell and Developmental Biology
Assuntos:
IVM
NAT10
N4-acetylcytidine
post-transcriptional modulation
RNA modification
oocyte
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2021.704341/full
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