Hyperglycemia disturbs trophoblast functions and subsequently leads to failure of uterine spiral artery remodeling
Uterine spiral artery remodeling is necessary for fetal growth and development as well as pregnancy outcomes. During remodeling, trophoblasts invade the arteries, replace the endothelium and disrupt the vascular smooth muscle, and are strictly regulated by the local microenvironment. Elevated glucos...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2023-04-01
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| coleção: | Frontiers in Endocrinology |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1060253/full |
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