Modified N-acyl-L-homoserine lactone compounds abrogate Las-dependent quorum-sensing response in human pathogen Pseudomonas aeruginosa

Quorum sensing (QS) is a mode of cell–cell communication that bacteria use to sense population density and orchestrate collective behaviors. The common opportunistic human pathogen Pseudomonas aeruginosa employs QS to regulate a large set of genes involved in virulence and host–pathogen interactions...

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Главные авторы:	Flavio Ballante, Maria V. Turkina, Maria Ntzouni, Karl-Eric Magnusson, Elena Vikström
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-10-01
Серии:	Frontiers in Molecular Biosciences
Предметы:	Pseudomonas aeruginosa quorum sensing antivirulence strategy small-molecule probes N-acyl-L-homoserine lactone LasR
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fmolb.2023.1264773/full
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