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Characterization of hydrophobic peptides in the presence of detergent by photoionization mass spectrometry.

The characterization of membrane proteins is still challenging. The major issue is the high hydrophobicity of membrane proteins that necessitates the use of detergents for their extraction and solubilization. The very poor compatibility of mass spectrometry with detergents remains a tremendous obsta...

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Autors principals: Aïcha Bagag, Jean-Michel Jault, Nazha Sidahmed-Adrar, Matthieu Réfrégiers, Alexandre Giuliani, François Le Naour
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2013-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3827311?pdf=render
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