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Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability

Raloxifene (RLX) is a second-generation selective estrogen receptor modulator used to treat osteoporosis in postmenopausal women. RLX fails to be developed into injectable dosage forms due to poor solubility. Although oral formulations are clinically available, the lower bioavailability (<2%) embarr...

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Détails bibliographiques
Auteurs principaux: Xinhui Du, Na Gao, Xiaoyong Song
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis Group 2021-01-01
Collection:Drug Delivery
Sujets:
Accès en ligne:http://dx.doi.org/10.1080/10717544.2021.1872742
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