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Metformin Induces MeCP2 in the Hippocampus of Male Mice with Sex-Specific and Brain-Region-Dependent Molecular Impact

Rett Syndrome (RTT) is a progressive X-linked neurodevelopmental disorder with no cure. RTT patients show disease-associated symptoms within 18 months of age that include developmental regression, progressive loss of useful hand movements, and breathing difficulties, along with neurological impairme...

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Principais autores: Khatereh Saei Arezoumand, Chris-Tiann Roberts, Mojgan Rastegar
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2024-04-01
סדרה:Biomolecules
נושאים:
Rett Syndrome
RTT
MeCP2
DNA methylation
adult brain
metformin
גישה מקוונת:https://www.mdpi.com/2218-273X/14/4/505
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