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Mechanism by which Icariin suppresses pulmonary metastasis in triple-negative breast cancer through downregulation of the SPDL1/JAK2/STAT3 signaling pathway

Abstract Triple-negative breast cancer (TNBC), a distinct subtype of breast cancer, is characterized by the concurrent absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) in tumor tissues. This molecular phenotype renders current endocri...

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Principais autores: Zengyou Xiao, Zean Yang, Xiaotong Li, Xin Chen, Jiaxian Li, Yujie He, Wei Li, Jie Wang
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2026-02-01
סדרה:Cancer Cell International
נושאים:
Icariin
Triple-Negative Breast Cancer
SPDL1
JAK2/STAT3
גישה מקוונת:https://doi.org/10.1186/s12935-026-04216-3
תגים: הוספת תג
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