Microglia morphological response to mesenchymal stromal cell extracellular vesicles demonstrates EV therapeutic potential for modulating neuroinflammation

Abstract Background Mesenchymal stromal cell derived extracellular vesicles (MSC-EVs) are a promising therapeutic for neuroinflammation. MSC-EVs can interact with microglia, the resident immune cells of the brain, to exert their immunomodulatory effects. In response to inflammatory cues, such as cyt...

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Autores principales:	Kanupriya R. Daga, Andrew M. Larey, Maria G. Morfin, Kailin Chen, Sara Bitarafan, Jana M. Carpenter, Hannah M. Hynds, Kelly M. Hines, Levi B. Wood, Ross A. Marklein
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-10-01
Colección:	Journal of Biological Engineering
Materias:	Microglia Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) Morphology Secretion Proteomics Lipidomics
Acceso en línea:	https://doi.org/10.1186/s13036-024-00449-w
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