Protective Effects of Dexmedetomidine on the Vascular Endothelial Barrier Function by Inhibiting Mitochondrial Fission via ER/Mitochondria Contact

The damage of vascular endothelial barrier function induced by sepsis is critical in causing multiple organ dysfunctions. Previous studies showed that dexmedetomidine (Dex) played a vital role in protecting organ functions. However, whether Dex participates in protecting vascular leakage of sepsis a...

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Detalhes bibliográficos

Principais autores:	Han She, Yu Zhu, Haoyue Deng, Lei Kuang, He Fang, Zisen Zhang, Chenyang Duan, Jiaqing Ye, Jie Zhang, Liangming Liu, Yi Hu, Tao Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-03-01
coleção:	Frontiers in Cell and Developmental Biology
Assuntos:	sepsis Drp1 ER-MITO contact dexmedetomidine vascular endothelial barrier function
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2021.636327/full
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