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Expansion and characterization of human limbus-derived stromal/mesenchymal stem cells in xeno-free medium for therapeutic applications

Abstract Background Mesenchymal stem cells (MSCs) have been proven to prevent and clear corneal scarring and limbal stem cell deficiency. However, using animal-derived serum in a culture medium raises the ethical and regulatory bar. This study aims to expand and characterize human limbus-derived str...

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Principais autores: Abhishek Sahoo, Mukesh Damala, Jilu Jaffet, Deeksha Prasad, Sayan Basu, Vivek Singh
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2023-04-01
Series:Stem Cell Research & Therapy
Assuntos:
hLMSCs
Xeno-free media
Corneal scarring
Regenerative medicine
Therapeutic applications
Acceso en liña:https://doi.org/10.1186/s13287-023-03299-3
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