Oxygen conditions oscillating between hypoxia and hyperoxia induce different effects in the pulmonary endothelium compared to constant oxygen conditions

Abstract The pulmonary endothelium is an immediate recipient of high oxygen concentrations upon oxygen therapy and mediates down‐stream responses. Cyclic collapse and reopening of atelectatic lung areas during mechanical ventilation with high fractions of inspired oxygen result in the propagation of...

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Hauptverfasser:	Peter Wohlrab, Michael Johann Danhofer, Wolfgang Schaubmayr, Akos Tiboldi, Katharina Krenn, Klaus Markstaller, Roman Ullrich, Klaus Ulrich Klein, Verena Tretter
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2021-02-01
Schriftenreihe:	Physiological Reports
Schlagworte:	hyperoxia intermittent hyperoxia lung microvascular endothelial cells oxygen oscillations
Online-Zugang:	https://doi.org/10.14814/phy2.14590
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