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Reevaluating Yeast Metabolism: Understanding Crabtree–Warburg Effects Differences with the <i>snf1∆</i> Strain as a New Model of the Warburg Effect

The Crabtree and Warburg effects both involve elevated glycolytic flux and fermentation under aerobic conditions, yet their regulatory bases differ fundamentally. In the Crabtree effect, high-glucose concentrations suppress mitochondrial respiration, redirecting carbon flux toward fermentation. In c...

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Principais autores: Gerardo M. Nava, Karla I. Lira-de León, David G. García-Gutiérrez, Vanessa Sánchez-Quezada, Luis Alberto Madrigal-Perez
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2026-01-01
coleção:Applied Sciences
Assuntos:
warburg effect
crabtree effect
<i>Saccharomyces cerevisiae</i>
fermentation
mitochondrial respiration
<i>SNF1</i>
Acesso em linha:https://www.mdpi.com/2076-3417/16/3/1311
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