Lysophosphatidylcholine-induced mitochondrial fission contributes to collagen production in human cardiac fibroblasts[S]

Lysophosphatidylcholine (LPC) may accumulate in the heart to cause fibrotic events, which is mediated through fibroblast activation and collagen accumulation. Here, we evaluated the mechanisms underlying LPC-mediated collagen induction via mitochondrial events in human cardiac fibroblasts (HCFs), co...

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Detalhes bibliográficos

Principais autores:	Hui-Ching Tseng, Chih-Chung Lin, Li-Der Hsiao, Chuen-Mao Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2019-09-01
coleção:	Journal of Lipid Research
Assuntos:	heart cell signaling extracellular matrix inflammation lysophospholipid cardiac fibrosis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520323191
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