Divergent B-cell repertoire remodelling by mRNA, DNA and live attenuated vaccines in fish

Abstract Vaccination is critical for the future of aquaculture, and nucleic acid vaccines have a major potential for fighting emerging fish infectious diseases, yet their mechanisms remain poorly understood. We compared B-cell responses induced by an mRNA, a DNA, and an attenuated vaccine, all encod...

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Autores principales:	Dean Porter, Catherine Collins, Andrea Mazzolini, Luc Jouneau, Vanessa Mhanna, Céline Coiffier, Mathilde Peruzzi, Yan Jaszczyszyn, Encarnita Mariotti-Ferrandiz, Francois Huetz, Bertrand Collet, Thierry Mora, Aleksandra M. Walczak, Bernard Verrier, Pierre Boudinot
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-07-01
Colección:	npj Vaccines
Acceso en línea:	https://doi.org/10.1038/s41541-025-01232-8
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