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Bioinformatics analysis of mRNA and miRNA microarray to identify the key miRNA-mRNA pairs in cisplatin-resistant ovarian cancer

Abstract Background Ovarian cancer (OC) is a gynecological malignancy with the highest mortality rate. Cisplatin (DDP) based chemotherapy is a standard strategy for ovarian cancer. Despite good response rates for initial chemotherapy, almost 80% of the patients treated with DDP based chemotherapy wi...

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Autores principales: Bai Xue, Shupeng Li, Xianyu Jin, Lifeng Liu
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2021-04-01
Colección:BMC Cancer
Materias:
Cisplatin-resistant
Ovarian cancer
miRNA
mRNA
Bioinformatics analysis
miRNA-mRNA pairs
Acceso en línea:https://doi.org/10.1186/s12885-021-08166-z
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