Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast

Most eukaryotic mRNAs accommodate alternative sites of poly(A) addition in the 3’ untranslated region in order to regulate mRNA function. Here, we present a systematic analysis of 3’ end formation factors, which revealed 3’UTR lengthening in response to a loss of the core machinery, whereas a loss o...

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Detalhes bibliográficos

Principais autores:	Rachael Emily Turner, Paul F Harrison, Angavai Swaminathan, Calvin A Kraupner-Taylor, Belinda J Goldie, Michael See, Amanda L Peterson, Ralf B Schittenhelm, David R Powell, Darren J Creek, Bernhard Dichtl, Traude H Beilharz
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2021-07-01
coleção:	eLife
Assuntos:	alternative polyadenylation transcription elongation cleavage polyadenylation cordycepin mycophenolic acid
Acesso em linha:	https://elifesciences.org/articles/65331
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