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Analyses of emerging macrocyclic lactone resistance: Speed and signature of ivermectin and moxidectin selection and evidence of a shared genetic locus.

Subtherapeutic treatment or 'underdosing' is considered a common problem in the control of parasitic helminths of animals and people and can hasten the emergence of anthelmintic resistance. Increasing reliance on the long-acting macrocyclic lactone, moxidectin, in both veterinary and medical setting...

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Detalhes bibliográficos
Principais autores: Jennifer McIntyre, Alison Morrison, Kirsty Maitland, Eileen Devaney, James A Cotton, Collette Britton, Ray M Kaplan, Dave Bartley, Roz Laing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2025-10-01
coleção:PLoS Pathogens
Acesso em linha:https://doi.org/10.1371/journal.ppat.1013578
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