An Orthogonal Protection Strategy for the Synthesis of Conotoxins Containing Three Disulfide Bonds
Disulfide bonds are crucial for stabilizing bioactive peptides such as conotoxins. We have developed a method for synthesizing conotoxins with three disulfide bonds using Mob, Trt, and Acm protection groups for regionally selective synthesis. This approach enabled the efficient synthesis of peptides...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI AG
2025-04-01
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| Serie: | Marine Drugs |
| Soggetti: | |
| Accesso online: | https://www.mdpi.com/1660-3397/23/4/168 |
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