Tumour sampling conditions perturb the metabolic landscape of clear cell renal cell carcinoma

Abstract Human isotopic tracer studies are key for in vivo studies of cancer metabolism. Yet, the effects of sampling conditions on the tissue metabolome remain understudied. Here, we perform a 13C-glucose study coupled with metabolomic, transcriptomic, and proteomic profiling in patients with clear...

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Hlavní autoři:	Cissy Yong, Christina Schmidt, Ming Yang, Alexander Von Kriegsheim, Anne Y. Warren, Shubha Anand, James N. Armitage, Antony C. P. Riddick, Thomas J. Mitchell, Vishal Patil, Kourosh Saeb-Parsy, Sakari Vanharanta, Grant D. Stewart, Christian Frezza
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-11-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-025-65676-1
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