The C-terminal region of Net1 is an activator of RNA polymerase I transcription with conserved features from yeast to human.
RNA polymerase I (Pol I) synthesizes ribosomal RNA (rRNA) in all eukaryotes, accounting for the major part of transcriptional activity in proliferating cells. Although basal Pol I transcription factors have been characterized in diverse organisms, the molecular basis of the robust rRNA production in...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2019-02-01
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| Serier: | PLoS Genetics |
| Online adgang: | http://europepmc.org/articles/PMC6415870?pdf=render |
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