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Amino acid decarboxylation preserves Salmonella fitness during phagocyte-derived oxidative stress

ABSTRACT Successful establishment of infection by non-typhoidal Salmonella depends upon its ability to resist the antimicrobial defenses of the host innate immune response. To withstand the membrane depolarization that potentiates the killing activity of reactive oxygen species (ROS) produced by the...

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Main Authors: Alyssa Margolis, Lin Liu, Ju-Sim Kim, Steffen Porwollik, Michael McClelland, Andrés Vázquez-Torres
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2025-01-01
Series:mBio
Subjects:
Salmonella
pathogenesis
metabolism
host-pathogen interactions
macrophages
oxidative stress
Online Access:https://journals.asm.org/doi/10.1128/mbio.03147-25
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