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Potential of notochordal cells within injectable biomaterials to promote intervertebral disc regeneration

Low back pain is the leading cause of disability worldwide and is strongly associated with degeneration of the intervertebral disc (IVD). During degeneration the nucleus pulposus (NP) in the core of the IVD, is affected by altered matrix synthesis, increased degradation, and cell loss. Strategies co...

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Principais autores: RJ Williams, S Basatvat, TC Schmitz, R Janani, C Sammon, K Benz, K Ito, MA Tryfonidou, JW Snuggs, CL Le Maitre
Format: Artigo
Sprog:Inglês
Udgivet: Forum Multimedia Publishing LLC 2024-03-01
Serier:European Cells & Materials
Fag:
ivd degeneration
disc degeneration
biomaterial
notochordal cells
hydrogels
hyaluronic acid
Online adgang:https://www.ecmjournal.org/papers/vol047/vol047a03.php
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