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Biological Evaluation of Triorganotin Derivatives as Potential Anticancer Agents

Metal-derived platinum complexes are widely used to treat solid tumors. However, systemic toxicity and tumor resistance to these drugs encourage further research into similarly effective compounds. Among others, organotin compounds have been shown to inhibit cell growth and induce cell death and aut...

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Main Authors: Valeria Stefanizzi, Antonella Minutolo, Elena Valletta, Martina Carlini, Franca M. Cordero, Anna Ranzenigo, Salvatore Pasquale Prete, Daniel Oscar Cicero, Erica Pitti, Greta Petrella, Claudia Matteucci, Francesca Marino-Merlo, Antonio Mastino, Beatrice Macchi
Format: Artigo
Language:Inglês
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
tin
organotin derivatives
cytotoxicity
growth inhibition
tumor cells
cell death
Online Access:https://www.mdpi.com/1420-3049/28/9/3856
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