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Targeting kinases with precision

Cancer genomics and mechanistic studies have revealed that heterogeneous mutations within a single kinase can result in a variety of activation mechanisms. The challenge has been to match these insights with tailored drug discovery strategies to yield potent, highly selective drugs. With optimized d...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Alexandra K. Gardino, Erica K. Evans, Joseph L. Kim, Natasja Brooijmans, Brian L. Hodous, Beni Wolf, Christoph Lengauer
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Taylor & Francis Group 2018-05-01
Rangatū:Molecular & Cellular Oncology
Ngā marau:
Urunga tuihono:http://dx.doi.org/10.1080/23723556.2018.1435183
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