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Resveratrol Analogues as Dual Inhibitors of Monoamine Oxidase B and Carbonic Anhydrase VII: A New Multi-Target Combination for Neurodegenerative Diseases?

Neurodegenerative diseases (NDs) are described as multifactorial and progressive syndromes with compromised cognitive and behavioral functions. The multi-target-directed ligand (MTDL) strategy is a promising paradigm in drug discovery, potentially leading to new opportunities to manage such complex...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Simone Carradori, Marialuigia Fantacuzzi, Alessandra Ammazzalorso, Andrea Angeli, Barbara De Filippis, Salvatore Galati, Anél Petzer, Jacobus P. Petzer, Giulio Poli, Tiziano Tuccinardi, Mariangela Agamennone, Claudiu T. Supuran
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-11-01
Schriftenreihe:Molecules
Schlagworte:
resveratrol analogs
phenols
monoamine oxidases
carbonic anhydrases
molecular modeling
neurodegenerative diseases
Online-Zugang:https://www.mdpi.com/1420-3049/27/22/7816
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