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Allosteric inhibitors of the NS3 protease from the hepatitis C virus.

The nonstructural protein 3 (NS3) from the hepatitis C virus processes the non-structural region of the viral precursor polyprotein in infected hepatic cells. The NS3 protease activity has been considered a target for drug development since its identification two decades ago. Although specific inhib...

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Autori principali: Olga Abian, Sonia Vega, Javier Sancho, Adrian Velazquez-Campoy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:https://doi.org/10.1371/journal.pone.0069773
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