Characterization of extracellular vesicle-associated DNA and proteins derived from organotropic metastatic breast cancer cells

Abstract Background While primary breast cancer (BC) is often effectively managed, metastasis remains the primary cause of BC-related fatalities. Gaps remain in our understanding of the mechanisms regulating cancer cell organotropism with predilection to specific organs. Unraveling mediators of site...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Amélie Nadeau, Thupten Tsering, Mohamed Abdouh, Laura Kienzle, Jenna Cleyle, Lorne Taylor, Noélie Douanne, Kyle Dickinson, Peter M. Siegel, Julia V. Burnier
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-05-01
Schriftenreihe:	Journal of Experimental & Clinical Cancer Research
Schlagworte:	Extracellular vesicles Metastatic breast cancer Organotropism Proteomics DNA Biomarkers
Online-Zugang:	https://doi.org/10.1186/s13046-025-03418-3
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