D-Arg0-Bradykinin-Arg-Arg, a Latent Vasoactive Bradykinin B2 Receptor Agonist Metabolically Activated by Carboxypeptidases

We previously reported hypotensive and vasodilator effects from C-terminally extended bradykinin (BK) sequences that behave as B2 receptor (B2R) agonists activated by vascular or plasma peptidases. D-Arg0-BK-Arg-Arg (r-BK-RR) is a novel prodrug peptide hypothetically activated by two catalytic cycle...

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Bibliografiset tiedot

Päätekijät:	Hélène Bachelard, Xavier Charest-Morin, François Marceau
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2018-03-01
Sarja:	Frontiers in Pharmacology
Aiheet:	bradykinin angiotensin converting enzyme arginine carboxypeptidases B2 receptors hypotension D-Arg0-BK-Arg-Arg
Linkit:	http://journal.frontiersin.org/article/10.3389/fphar.2018.00273/full
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