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Polymer-Nanodiscs as a Novel Alignment Medium for High-Resolution NMR-Based Structural Studies of Nucleic Acids

Residual dipolar couplings (RDCs) are increasingly used for high-throughput NMR-based structural studies and to provide long-range angular constraints to validate and refine structures of various molecules determined by X-ray crystallography and NMR spectroscopy. RDCs of a given molecule can be meas...

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Principais autores: Bankala Krishnarjuna, Thirupathi Ravula, Edgar M. Faison, Marco Tonelli, Qi Zhang, Ayyalusamy Ramamoorthy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-11-01
coleção:Biomolecules
Assuntos:
nanodiscs
NMR
magnetic alignment
RNA
residual dipolar couplings
Acesso em linha:https://www.mdpi.com/2218-273X/12/11/1628
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