Modeling metastasis and predicting drug response with malignant effusion-derived organoids: a systematic review and quantitative assessment

Abstract Background Malignant effusions provide a critical window into metastatic biology. Malignant effusion-derived organoids (ME-PDTOs) hold promise for modeling metastasis and predicting drug response, but the evidence remains fragmented. This systematic review aims to synthesize current evidenc...

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Autors principals:	Jingyu Peng, Shuting Tian, Li Liu, Yifang Deng
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-05-01
Col·lecció:	Journal of Translational Medicine
Matèries:	Patient-derived organoids Malignant effusions Tumor metastasis Intratumoral heterogeneity Personalized medicine
Accés en línia:	https://doi.org/10.1186/s12967-026-08107-z
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