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Proinflammatory and Cancer-Promoting Pathobiont <i>Fusobacterium nucleatum</i> Directly Targets Colorectal Cancer Stem Cells

Intestinal bacterial communities participate in gut homeostasis and are recognized as crucial in bowel inflammation and colorectal cancer (CRC). <i>Fusobacterium nucleatum</i> (<i>Fn</i>), a pathobiont of the oral microflora, has recently emerged as a CRC-associated microbe linked to disease progres...

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Hlavní autoři: Virve Cavallucci, Ivana Palucci, Marco Fidaleo, Antonella Mercuri, Letizia Masi, Valeria Emoli, Giada Bianchetti, Micol Eleonora Fiori, Gilad Bachrach, Franco Scaldaferri, Giuseppe Maulucci, Giovanni Delogu, Giovambattista Pani
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-09-01
Edice:Biomolecules
Témata:
colorectal cancer
cancer stem cells
microbiota
fusobacterium nucleatum
tumor microenvironment
tumor spheroids
On-line přístup:https://www.mdpi.com/2218-273X/12/9/1256
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