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Gender differences in the plasma profiles of proprotein convertase subtilisin/kexin-type 9 (PCSK9), soluble low-density lipoprotein receptor (sLDLR), total cholesterol, and triglycerides in patients with colorectal cancer liver metastases: diagnostic and prognostic implications

Abstract Background Proprotein convertase subtilisin/kexin-type 9 (PCSK9) and soluble low-density lipoprotein receptor (sLDLR) are circulating proteins that down regulate LDLR-mediated uptake of plasma LDL-cholesterol into cells. In healthy individuals, plasma PCSK9 and sLDLR levels correlate with t...

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Principais autores: Clara Lafortune, Yara Haddad, Mieczyslaw Marcinkiewicz, Michel Chrétien, Simon Turcotte, Majambu Mbikay
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-05-01
coleção:Lipids in Health and Disease
Assuntos:
PCSK9
Soluble LDLR
Colorectal cancer liver metastasis
Cholesterol
Triglycerides
Biomarkers
Acesso em linha:https://doi.org/10.1186/s12944-026-02981-8
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