A quantitative model for the rate-limiting process of UGA alternative assignments to stop and selenocysteine codons.

Ambiguity in genetic codes exists in cases where certain stop codons are alternatively used to encode non-canonical amino acids. In selenoprotein transcripts, the UGA codon may either represent a translation termination signal or a selenocysteine (Sec) codon. Translating UGA to Sec requires selenium...

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Autores principales:	Yen-Fu Chen, Hsiu-Chuan Lin, Kai-Neng Chuang, Chih-Hsu Lin, Hsueh-Chi S Yen, Chen-Hsiang Yeang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2017-02-01
Colección:	PLoS Computational Biology
Acceso en línea:	https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005367&type=printable
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