Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model

Abstract Atypical Scrapie, which is not linked to epidemics, is assumed to be an idiopathic spontaneous prion disease in small ruminants. Therefore, its occurrence is unlikely to be controlled through selective breeding or other strategies as it is done for classical scrapie outbreaks. Its spontaneo...

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Autors principals:	Enric Vidal, Manuel A. Sánchez-Martín, Hasier Eraña, Sonia Pérez Lázaro, Miguel A. Pérez-Castro, Alicia Otero, Jorge M. Charco, Belén Marín, Rafael López-Moreno, Carlos M. Díaz-Domínguez, Mariví Geijo, Montserrat Ordóñez, Guillermo Cantero, Michele di Bari, Nuria L. Lorenzo, Laura Pirisinu, Claudia d’Agostino, Juan María Torres, Vincent Béringue, Glenn Telling, Juan J. Badiola, Martí Pumarola, Rosa Bolea, Romolo Nonno, Jesús R. Requena, Joaquín Castilla
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-12-01
Col·lecció:	Acta Neuropathologica Communications
Matèries:	Atypical Scrapie Spontaneous Prion disease Isoleucine
Accés en línia:	https://doi.org/10.1186/s40478-022-01477-7
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