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A neural strategy for the inference of SH3 domain-peptide interaction specificity

<p>Abstract</p> <p>Background</p> <p>The SH3 domain family is one of the most representative and widely studied cases of so-called Peptide Recognition Modules (PRM). The polyproline II motif PxxP that generally characterizes its ligands does not reflect the complex interaction spectrum of the over 1...

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Principais autores: Ausiello Gabriele, Via Allegra, Ferraro Enrico, Helmer-Citterich Manuela
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2005-12-01
Serier:BMC Bioinformatics
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