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Cell-dependent antithrombotic effect of tranexamic acid

BackgroundTranexamic acid (TXA) is a synthetic lysine analog that inhibits fibrinolysis by blocking lysine-binding sites on plasminogen and plasmin. Although early therapeutic TXA reduces bleeding mortality in major trials, prophylactic benefit appears context- and timing-dependent. TXA is generally...

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Main Authors: Kata Balog Virág, Petra Csikós, Alexandra Raska, Barbara Baráth, Kristóf Molnár, Natalia Nikolova, Kiril Tenekedjiev, Krasimir Kolev, Nikolett Wohner
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2026-05-01
Series:Frontiers in Immunology
Subjects:
antithrombotic action
fibrinolysis
immunothrombosis
plasminogen
tranexamic acid
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1820813/full
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