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Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Abstract Synovial inflammation represents a hallmark pathological process in osteoarthritis (OA), yet the cellular drivers orchestrating this response remain incompletely defined. Through single‐cell transcriptomic profiling of human OA synovial tissues, a distinct subset of CD74⁺ macrophages is ide...

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Bibliografiska uppgifter
Huvudupphov: Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui
Materialtyp: Artigo
Språk:Inglês
Utgiven: Wiley 2026-02-01
Serie:Advanced Science
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Länkar:https://doi.org/10.1002/advs.202508472
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