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Pharmacological S100A8/A9-targeting blockade attenuates toluene diisocyanate-induced mixed granulocytic asthma

Background and objective: Mixed granulocytic asthma (MGA) is clinically characterized by poor responsiveness to corticosteroid and a high predisposition of refractory asthma. While emerging evidence has implicated S100A8/A9 in the pathogenesis of asthma, its specific role in MGA remains unexplored....

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Principais autores: Shuyu Chen, Yuanyuan Liu, Shengguo Liu, Wei Ma, Zhou Cai, Linlin Zheng, Kai Yang, Lingwei Wang, Yingyun Fu, Zhengqiang He, Rongchang Chen
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2026-01-01
Series:Ecotoxicology and Environmental Safety
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0147651326000072
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