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Design, synthesis, and multitarget evaluation of novel quinolone-based heterocyclic derivatives as acetyl cholinesterase inhibitors for Alzheimer’s disease therapy

Abstract Background Alzheimer disease is progressive neurodegenerative disorder with mild memory loss and cognitive impairment. Neurodegenerative diseases in which the decrease in the acetylcholine is observed are growing worldwide. Ten quinolone containing compounds were synthesized and screened fo...

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Bibliografski detalji
Glavni autori: Anjali M. Dobariya, Vipul M. Vaghela, Sheetal Buddhadev, Bhupendra Prajapati
Format: Artigo
Jezik:Inglês
Izdano: SpringerOpen 2026-03-01
Serija:Future Journal of Pharmaceutical Sciences
Teme:
Online pristup:https://doi.org/10.1186/s43094-026-00967-y
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