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Integrating bulk and single-cell RNA sequencing analysis to reveal characterization of mechanical stimulus-related genes and prognostic signatures in breast cancer

Abstract Objectives To identify molecular clusters and establish a scoring model based on mechanical stimulus-related genes (MSRGs) for predicting the prognosis of breast cancer patients and understanding the role of mechanical stimuli in the breast tumor microenvironment (TME). Methods We utilized...

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Wedi'i Gadw mewn:
Prif Awduron: Ze Yang, Haifeng Lou, Yuqiao Huang, Lingyun Guo, Yingfei Huang, Gao Zhu, Jingjia Li, Yindan Lin, Jiang Zhu, Yandi Sun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2025-11-01
Cyfres:Breast Cancer Research
Pynciau:
Mechanical stimulus
Breast cancer
Prognostic signature
Tumor immune microenvironment
Mynediad Ar-lein:https://doi.org/10.1186/s13058-025-02130-6
Tagiau: Ychwanegu Tag
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