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The role of elastin on the mechanical properties of the anterior leaflet in porcine tricuspid valves

Elastin is present in the extracellular matrix (ECM) of connective tissues, and its mechanical properties are well documented. In Marfan syndrome, however, the inability to properly code for the protein fibrillin-1 prematurely leads to the degradation and loss of elastin fiber integrity in the ECM....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Samuel D. Salinas, Yasmeen M. Farra, Keyvan Amini Khoiy, James Houston, Chung-Hao Lee, Chiara Bellini, Rouzbeh Amini
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2022-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106221/?tool=EBI
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