f-SPION-mediated magnetic stimulation induces reparative Schwann cell reprogramming via cytoskeletal dynamics - gated activation of Piezo1

Abstract Background The remarkable intrinsic regenerative capacity of peripheral nerves following injury is largely attributed to the phenotypic plasticity of Schwann cells (SCs) and their ability to transition into a repair-supportive state (rSCs). Transcriptional reprogramming of SCs into this rep...

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Detalhes bibliográficos

Principais autores:	Ting Liu, Mingxi Yang, Wantao Tian, Jingyan Ren, Laijin Lu, Yang Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-02-01
coleção:	Journal of Nanobiotechnology
Assuntos:	Peripheral nerve injury (PNI) Repair Schwann cells (rSCs) Reprogramming Mechanobiology Magnetomechanical neuromodulation Mechanotransduction
Acesso em linha:	https://doi.org/10.1186/s12951-026-04105-x
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