G-CSF/NAMPT signaling drives neutrophil dysfunction and enhances bacterial infection susceptibility in cancer patients

Abstract Despite advancements in cancer therapies, bacterial complications remain a major challenge, delaying treatment and worsening outcomes. While immunosuppressive therapies and prolonged hospitalizations contribute, they do not fully explain the elevated infection risk in cancer patients. Here...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Ekaterina Pylaeva, Lea Tollrian, Jana Riedesel, Olga Shevchuk, Ilona Thiel, Irem Ozel, Nastassia Kabankova, Hannah Voß, Bente Siebels, Hartmut Schlüter, Corinna Haist, Helmut Hanenberg, Stefan Mattheis, Cornelius Kürten, Markus Sperandio, Jan Kehrmann, Daniel Robert Engel, Stephan Lang, Jadwiga Jablonska
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Nature Portfolio 2025-12-01
Σειρά:	Nature Communications
Διαθέσιμο Online:	https://doi.org/10.1038/s41467-025-67471-4
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