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Biomarker Periodic Repolarization Dynamics Indicates Enhanced Risk for Arrhythmias and Sudden Cardiac Death in Myocardial Infarction in Pigs

Background Periodic repolarization dynamics (PRD) is an electrocardiographic biomarker that captures repolarization instability in the low frequency spectrum and is believed to estimate the sympathetic effect on the ventricular myocardium. High PRD indicates an increased risk for postischemic sudden...

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Main Authors: Julia Bauer, Julia Vlcek, Valerie Pauly, Nora Hesse, Ruibing Xia, Li Mo, Aparna Sharma Chivukula, Hannes Villgrater, Marie Dressler, Bianca Hildebrand, Eckhard Wolf, Konstantinos D. Rizas, Axel Bauer, Stefan Kääb, Philipp Tomsits, Dominik Schüttler, Sebastian Clauss
Format: Artigo
Language:Inglês
Published: Wiley 2024-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
autonomic remodeling
ischemic heart failure
periodic repolarization dynamics
pig model
sudden cardiac death
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.032405
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