Combination of a Latency-Reversing Agent With a Smac Mimetic Minimizes Secondary HIV-1 Infection in vitro

Latency-reversing agents (LRAs) are considered a potential tool to cure human immunodeficiency virus type 1 (HIV-1) infection, but when they are taken alone, virus production by reactivated cells and subsequent infection will occur. Hence, it is crucial to simultaneously take appropriate measures to...

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Principais autores:	Shin-ichiro Hattori, Kouki Matsuda, Kiyoto Tsuchiya, Hiroyuki Gatanaga, Shinichi Oka, Kazuhisa Yoshimura, Hiroaki Mitsuya, Kenji Maeda
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-09-01
coleção:	Frontiers in Microbiology
Assuntos:	HIV latency-reversing agent Smac mimetic birinapant PKC activator caspase-3
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fmicb.2018.02022/full
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