PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina
Current gene therapies predominantly use small, strong, and readily available ubiquitous promoters. However, as the field matures, the availability of small, cell-specific promoters would be greatly beneficial. Here we design seven small promoters from the human paired box 6 (PAX6) gene and test the...
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| Autori principali: | , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2016-01-01
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| Serie: | Molecular Therapy: Methods & Clinical Development |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2329050117300232 |
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