DNA Damage Induced by Alkylating Agents and Repair Pathways
The cytotoxic effects of alkylating agents are strongly attenuated by cellular DNA repair processes, necessitating a clear understanding of the repair mechanisms. Simple methylating agents form adducts at N- and O-atoms. N-methylations are removed by base excision repair, AlkB homologues, or nucleot...
שמור ב:
| Principais autores: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Wiley
2010-01-01
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| סדרה: | Journal of Nucleic Acids |
| גישה מקוונת: | http://dx.doi.org/10.4061/2010/543531 |
| תגים: |
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